Triple therapy versus sequential therapy for the first-line Helicobacter pylori eradication

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Triple therapy versus sequential therapy for the first-line Helicobacter pylori eradication

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Levofloxacin and proton pump inhibitor-based triple therapy versus standard triple first-line therapy for Helicobacter pylori eradication.

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First- and second-line Helicobacter pylori eradication with modified sequential therapy and modified levofloxacin-amoxicillin-based triple therapy

BACKGROUND Helicobacter pylori (H. pylori) treatment remains a challenge for physicians. Although highly effective, the standard sequential therapy fails in a certain number of patients. Moreover, the cure rate following a levofloxacin-amoxicillin second-line triple therapy seems to be decreasing. We tested the efficacy of modified 10-day sequential therapy, and an intensified levofloxacin-amox...

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rst-line therapy for Helicobacter pylori eradication

Materials and methods: Th is is a prospective, open-label, single-centre study. Th e study involved 86 consecutive patients with nonulcer dyspepsia. All patients were randomly assigned into 2 study groups at a 2:1 ratio using random sampling numbers. Th e fi rst group of patients were administered a sequential treatment: pantoprazole 2 × 40 mg and amoxicillin 2 × 1000 mg for the fi rst 7 days a...

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BACKGROUND/AIMS Eradication of Helicobacter pylori infection with standard triple therapy (TT) has declined primarily because of increased antibiotic resistance. Sequential therapy (ST) has been suggested as an alternative to TT for the first-line treatment of H. pylori. The purpose of this study was to compare the efficacy of ST with TT. METHODS This was a multicenter, randomized open-label ...

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ژورنال

عنوان ژورنال: BMC Gastroenterology

سال: 2017

ISSN: 1471-230X

DOI: 10.1186/s12876-017-0579-8